Symbol
Name
ID

Ticam1
TIR domain containing adaptor molecule 1
MGI:2147032

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased macrophage apoptosis

decreased splenocyte proliferation

impaired macrophage phagocytosis

increased neutrophil cell number

increased plasmacytoid dendritic cell number

decreased CD8-positive, alpha-beta T cell number

increased macrophage cell number

increased Ly6C high monocyte number

decreased Ly6C low monocyte number

impaired neutrophil recruitment

abnormal B cell physiology

abnormal B cell activation

decreased IgG2a level

decreased IgG level

abnormal NK cell physiology

impaired natural killer cell mediated cytotoxicity

abnormal NK T cell physiology

abnormal macrophage physiology

decreased macrophage cytokine production

decreased macrophage nitric oxide production

abnormal microglial cell physiology

Availability

Mouse Genotype

Ticam1^Lps2/Ticam1^Lps2

Ticam1^M2Btlr/Ticam1^M2Btlr

Ticam1^tm1Aki/Ticam1^tm1Aki

Ticam1^tm1Tsse/Ticam1^tm1Tsse

Ticam1^M2Btlr/Ticam1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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